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Cycloheximide-N-ethylethanoate

FKBP inhibitor
 
BML-IM100-0050 50 mg 353.00 USD
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FKBP12 inhibitor (IC50=4.4µM) with neuroregenerative properties. Does not inhibit protein synthesis.

Product Specification

Formula:C19H29NO6
 
MW:367.4
 
Purity:≥99% (TLC)
 
Appearance:White solid.
 
MeltingPoint:97°C
 
Solubility:Soluble in DMSO (15mg/ml) or ethanol (3 mg/ml).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Use/Stability:Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months.
 
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Product Literature References

Synthesis and cytotoxic evaluation of cycloheximide derivatives as potential inhibitors of FKBP12 with neuroregenerative properties: C. Christner, et al.; J. Med. Chem. 42, 3615 (1999), Abstract;

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