Supresses cell growth and promotes retinoic acid-induced cell differentiation in HL-60 cells. It is a known inhibitor of Wnt/β-Catenin signaling pathway.
Product Details
| Alternative Name: | 1-(3,5-Dichloro-2,6-dihydroxy-4-methoxyphenyl) hexan-1-one, Differentiation-inducing factor-1 |
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| Formula: | C13H16Cl2O4 |
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| MW: | 307.2 |
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| CAS: | 111050-72-7 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | Pale yellow solid. |
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| Solubility: | Soluble in ethanol. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Evolution of a novel cell type in Dictyostelia required gene duplication of a cudA-like transcription factor: K. Kin, et al.; Curr. Biol.
32, 428 (2022),
Abstract;
Autophagy dysfunction and ubiquitin-positive protein aggregates in Dictyostelium cells lacking Vmp1: J. Calvo-Garrido & R. Escalante; Autophagy
6, 99 (2010),
Abstract;
DIF-1, putative morphogen of D. discoideum, suppresses cell growth and promotes retinoic acid-induced cell differentiation in HL-60: Y. Kubohara, et al.; Biochem. Biophys. Res. Commun.
236, 418 (1997),
Abstract;
