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Raloxifene . HCl

Estrogen receptor inhibitor
 
BML-GR243-0050 50 mg 74.00 USD
 
BML-GR243-0500 500 mg 323.00 USD
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A selective estrogen receptor modulator (SERM). Displays anti-estrogen action along with anti-androgen action. In clinical use for prevention of postmenopausal osteoporosis. Reduces circulating levels of IL-6 and TNFα. Inhibits prostate carcinogenesis in transgenic rat model. May be useful for the prevention of hormone-related cancers.

Product Specification

Formula:C28H28ClNO4S
 
MW:510
 
CAS:82640-04-8
 
Purity:≥98% (TLC)
 
Identity:Determined by 1H-NMR and MS.
 
Appearance:Pale green solid.
 
Solubility:Soluble in methanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store reconsitituted solutions at -20°C for up to three months.
 
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Product Literature References

Prevention of hormone-related cancers: breast cancer: B. K. Dunn, et al.; J. Clin. Oncol. 23, 357 (2005), Abstract;
Raloxifene modulates interleukin-6 and tumor necrosis factor-alpha synthesis in vivo: results from a pilot clinical study: W. Gianni, et al.; J. Clin. Endocrinol. Metab. 89, 6097 (2004), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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