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Z-Guggulsterone

FXR inhibitor
 
BML-GR235-0005 5 mg 86.00 USD
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A guggul tree steroid well known for its lipid lowering properties. Acts as a selective antagonist at farnesoid X receptors (FXRs). Inhibits FXR transactivation (IC50=10µM).

Product Specification

Formula:C21H28O2
 
MW:312.5
 
CAS:39025-23-5
 
Purity:≥98%
 
Appearance:White solid.
 
Solubility:Soluble in DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
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Product Literature References

A natural product that lowers cholesterol as an antagonist ligand for FXR: N. L. Urizar, et al.; Science 296, 1703 (2002), Abstract;

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FXR
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FXR Ligand
FXR Inhibitor
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