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Diindolylmethane

Ah receptor antagonist
 
BML-GR207-0050 50 mg 68.00 USD
 
BML-GR207-0250 250 mg 279.00 USD
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A partial antagonist for the aryl hydrocarbon receptor. Induces apoptosis in human cancer cells. Activates cytochrome P-450 1A2.

Product Specification

Formula:C17H14N2
 
MW:246.3
 
CAS:1968-05-4
 
Purity:≥98% (HPLC)
 
Appearance:Off-white powder.
 
Solubility:Soluble in DMSO.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
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Product Literature References

Agonist and chemopreventative ligands induce differential transcriptional cofactor recruitment by aryl hydrocarbon receptor: E. V. Hestermann & M. Brown; Mol. Cell. Biol. 23, 7920 (2003), Abstract; Full Text
3,3'-Diindolylmethane induces CYP1A2 in cultured precision-cut human liver slices: B. G. Lake, et al.; Xenobiotica 28, 803 (1998), Abstract;
Indole-3-carbinol and diindolylmethane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cells: I. Chen, et al.; Biochem. Pharmacol. 51, 1069 (1996), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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