Retinoic acid analog which acts as a selective RAR agonist.
Product Details
Alternative Name: | Ro 13-7410, 4-[E-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetra-methyl-2-naphthalenyl)-1-propenyl]benzoic acid |
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Formula: | C24H28O2 |
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MW: | 348.5 |
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CAS: | 71441-28-6 |
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Purity: | ≥98% (HPLC) |
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Identity: | Determined by 1H-NMR. |
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Appearance: | White crystalline solid. |
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Solubility: | Soluble in DMSO or ethanol (with gentle warming). |
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Shipping: | Ambient Temperature |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
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1, Article number 7 (2016),
Application(s): Cell cultures, Immunofluorescence staining, and microscopy,
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9-cis retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of fas ligand and requires retinoic acid receptor and retinoid X receptor activation: R. P. Bissonnette, et al.; Mol. Cell Biol.
15, 5576 (1995),
Abstract;
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Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids: M. F. Boehm, et al.; J. Med. Chem.
37, 2930 (1994),
Abstract;