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4-Hydroxyphenylretinamide

Retinoic acid receptor ligand
 
BML-GR103-0005 5 mg 112.00 USD
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An analog of all trans retinoic acid that shows antiproliferative activity on cultured human breast cancer cells. Highly selective activator of retinoid receptors. Induces apoptosis in malignant hemopoietic cell lines.

Product Specification

Alternative Name:Fenretinide
 
Formula:C26H33NO2
 
MW:391.5
 
Source:Synthetic.
 
CAS:65646-68-6
 
Purity:≥97% (TLC)
 
Appearance:Orange solid.
 
Solubility:Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
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Product Literature References

Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses: F.S. Varghese, et al.; Antiviral Res. 126, 117 (2016), Application(s): Cell culture, Abstract;
4-Hydroxyphenyl retinamide is a highly selective activator of retinoid receptors: A. N. Fanjul, et al.; J. Biol. Chem. 271, 22441 (1996), Abstract; Full Text
Differential effects of N-(4-hydroxyphenyl)retinamide and retinoic acid on neuroblastoma cells: apoptosis versus differentiation: M. Ponzoni, et al.; Cancer Res. 55, 853 (1995), Abstract; Full Text
N-(4-hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid: D. Delia, et al.; Cancer Res. 53, 6036 (1993), Abstract;
Effect of retinyl acetate and 4-hydroxyphenylretinamide on initiation of chemically-induced mammary tumors: C. J. Grubbs, et al.; Anticancer Res. 10, 661 (1990), Abstract;
Effect of 4-hydroxyphenylretinamide and retinoic acid on proliferation and cell cycle of cultured human breast cancer cells: C. Marth, et al.; J. Natl. Cancer Inst. 75, 871 (1985), Abstract;

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