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GP antagonist-2

G protein antagonist
 
BML-G510-0001 1 mg Inquire for pricing
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Replaces Prod. #: ALX-165-001

Selective, competitive and reversible G-protein antagonist. Inhibits the activation of Gi or Go by M2 muscarinic cholinergic receptors (mAChR) and Gs by β-adrenergic receptors in reconstituted phospholipid vesicles. Inhibition is reversible and competitive with respect to receptor binding to G proteins. Substance P (Prod. No. ALX-167-003) related compound.

Product Specification

Alternative Name:G-protein antagonist 2
 
Identity:Determined by MS.
 
Sequence:H-Pyr-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2
 
Formula:C57H64N12O9S
 
MW:1093.3
 
Source:Synthetic.
 
Formulation:Lyophilized.
 
Purity:≥95% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in water or DMSO.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 

Product Literature References

G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding: H. Mukai, et al.; J. Biol. Chem. 267, 16237 (1992), Abstract; Full Text

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Substance P 

Neuropeptide
33507-63-0, ≥97% (HPLC) | Print as PDF
 
ALX-167-003-M001 1 mg 44.00 USD
 
ALX-167-003-M005 5 mg 153.00 USD
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