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4-Oxatetradecanoic acid

Myristate analog
 
BML-G232-0050 50 mg 336.00 USD
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4-Oxatetradecanoic acid is a myristate analog which has similar chain length but reduced hydrophobicity compared to myristate. It inhibits replication of human immunodeficiency virus I and is fungicidal for Cryptococcus neoformans. Its specific mechanism of action is not clear but it is believed to either inhibit the activity of N-myristoyltransferase or modulate the function of target acylated proteins.

Product Specification

Formula:C13H26O3
 
MW:230.3
 
Source:Synthetic.
 
CAS:7420-16-8
 
Purity:≥98% (TLC)
 
Appearance:Low melting white to off-white solid.
 
Solubility:Soluble in DMSO (25mg/ml) and ethanol (25mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at 0-4°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
BML-G232 structure
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BML-G232 structure

Product Literature References

4-oxatetradecanoic acid is fungicidal for Cryptococcus neoformans and inhibits replication of human immunodeficiency virus I: C.A. Langner, et al.; J. Biol. Chem. 267, 17159 (1992), Abstract; Full Text

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