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Farnesylthioacetic acid

Methyltransferase inhibitor
 
BML-G222-0005 5 mg 78.00 USD
 
BML-G222-0025 25 mg 301.00 USD
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Replaces Prod. #: ALX-290-004

FTA potently and specifically inhibits methyl esterification of farnesylated proteins such as the γ subunit of transducin (70% at 10µM). It does not act as a substrate for methyl transferase.

Product Specification

Alternative Name:FTA
 
Formula:C17H28O2S
 
MW:296.5
 
Source:Synthetic.
 
CAS:135784-48-4
 
Purity:≥98% (TLC)
 
Appearance:Yellow viscous oil.
 
Solubility:Soluble in DMSO (>25mg/ml) or 100% ethanol (>25mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Solutions are stable for up to 6 months when stored at -20°C.
 
Handling:Protect from light.
 
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Product Literature References

Activation of TRPA1 by farnesyl thiosalicylic acid: M. Maher, et al.; Mol. Pharmacol. 73, 1225 (2008), Abstract;
Identifying the recognition unit for G protein methylation: E.W. Tan, et al.; J. Biol. Chem. 266, 10719 (1991), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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