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Diphtheria toxin (Corynebacterium diphtheriae)

 
BML-G135-0001 1 mg 764.00 USD
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Product Specification

Source:From Corynebacterium diphtheriae.
 
EC:2.4.2.36
 
Concentration:1µg/µl
 
Formulation:Lyophilized.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Scientific Background:Elongation factor 2 (EF-2) catalyzes the GTP hydrolysis-dependent translocation reaction that is responsible for the movement of the ribosome along mRNA during protein synthesis. Diphtheria toxin catalyzed ADP-ribosylation of EF-2 inhibits the translocation reaction which halts protein synthesis and ultimately results in cell death. Diphtheria toxin is cell permeable and can translocate across endosomal membranes in response to low pH3.
 

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