Product Details
| Source: | From Vibrio cholerae. |
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| CAS: | 131096-89-4 |
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| UniProt ID: | P01556 |
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| Formulation: | Lyophilized. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Scientific Background: | The B subunit of cholera toxin attaches the native toxin to eukaryotic cell surfaces and facilitates the translocation of the A subunit. It does not possess any intrinsic ADP-ribosyltransferase activity. The high affinity and specificity of the B subunit for ganglioside GM1 makes it a novel tool for probing the involvement of GM1 on growth and differentiation of neuronal and other cells. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Blocking GARP-mediated activation of TGF-β1 did not alter innate or adaptive immune responses to bacterial infection or protein immunization in mice: M. Gaignage, et al.; Cancer Immunol. Immunother.
71, 1851 (2022),
Abstract;
The Effect of Solar Irradiated Vibrio cholerae on the Secretion of Pro-Inflammatory Cytokines and Chemokines by the JAWS II Dendritic Cell Line In Vitro: C.C. Ssemakalu, et al.; PLoS One
10, e0130190 (2015),
Application(s): Cell Culture,
Abstract;
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