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Virodhamine

Cannabinoid receptor ligand
 
BML-FA036-0005 5 mg 138.00 USD
 
BML-FA036-0025 25 mg 525.00 USD
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Replaces Prod. #: ALX-340-051

Endogenous cannabinoid which has been found to occur at concentrations 2 to 9 fold greater than anandamide in peripheral tissue. It acts as a full agonist at the CB2 receptor and an antagonist at the CB1 receptor.

Product Specification

Alternative Name:O-AEA, O-Arachidonoylethanolamine, Arachidonic acid-(2-aminoethyl)-ester, O-(2-aminoethyl)-5Z,8Z,11Z,14Z-eicosatetraenoic acid ester
 
Formula:C22H37NO2
 
MW:347.5
 
CAS:443129-35-9
 
Purity:≥98% (TLC)
 
Appearance:Yellow oil.
 
Solubility:Soluble in DMSO (45mg/ml), dimethyl formamide (40mg/ml) or ethanol (20mg/ml)
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -80°C and under an inert atmosphere.
 
Handling:Protect from oxygen. Keep under inert gas.
 
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Product Literature References

Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor: A.C. Porter, et al.; J. Pharmacol. Exp. Ther. 301, 1020 (2002), Abstract;
Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds: T. Sugiura, et al.; J. Biol. Chem. 274, 2794 (1999), Abstract;

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