Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Arachidonic acid (20:4, n-6)

Eicosanoid precursor and second messenger
 
BML-FA003-0100 100 mg 90.00 USD
 
BML-FA003-1000 1 g 251.00 USD
Do you need bulk/larger quantities?
 
Replaces Prod. #: ALX-340-004

Precursor to a large family of eicosanoids. Acts as a second messenger independent of metabolism. Retrograde messenger in long-term potentiation in the nervous system. Inhibits ras-GAP. Activator for several protein kinase C (PKC) isotypes.

Product Specification

Alternative Name:5Z,8Z,11Z,14Z-Eicosatetraenoic acid
 
Formula:C20H32O2
 
MW:304.5
 
CAS:506-32-1
 
MI:14: 765
 
RTECS:CE6675000
 
Purity:≥99% (TLC)
 
Appearance:Colorless oil.
 
Solubility:100mg/ml soluble in DMSO or dimethyl formamide; soluble in 100% ethanol (50mg/ml); sparingly soluble in basic aqueous buffers (1.7mg/ml). To prevent oxidation, the solvent should be purged with an inert gas.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Stable for 12 months after receipt when stored at -20°C. Keep aqueous solutions on ice and use within 12 hours.
 
Handling:Protect from light and oxygen.
 
BML-FA003 structure
Please mouse over
BML-FA003 structure

Product Literature References

Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C: W.A. Khan, et al.; Cell. Signal. 7, 171 (1995), Abstract;
Covalent binding of arachidonate to G protein alpha subunits of human platelets: H. Hallak, et al.; J. Biol. Chem. 269, 4713 (1994), Abstract; Full Text
Arachidonic acid-induced Ca2+ release from isolated sarcoplasmic reticulum: C. Dettbarn & P. Palade; Biochem. Pharmacol. 45, 1301 (1993), Abstract;
Nitric oxide and arachidonic acid modulation of calcium currents in postganglionic neurones of avian cultured ciliary ganglia: G. Khurana & M.R. Bennett; Br. J. Pharmacol. 109, 480 (1993), Abstract;
Role of fatty acids in signal transduction: modulators and messengers: C. Sumida, et al.; Prostaglandins Leukot. Essent. Fatty Acids 48, 117 (1993), Abstract;
The immediate activator of the NADPH oxidase is arachidonate not phosphorylation: L.M. Henderson, et al.; Eur. J. Biochem. 211, 157 (1993), Abstract;
A unique pool of free arachidonate serves as substrate for both cyclooxygenase and lipoxygenase in platelets: F. Chevy, et al.; Lipids 26, 1080 (1991), Abstract;
Arachidonic acid as a second messenger. Interactions with a GTP-binding protein of human neutrophils: S.B. Abramson, et al.; J. Immunol. 147, 231 (1991), Abstract;
Is arachidonic acid a retrograde messenger in long-term potentiation?: M.A. Lynch, et al.; Biochem. Soc. Trans. 19, 391 (1991), Abstract;
Regulation of Ras-GAP and the neurofibromatosis-1 gene product by eicosanoids: J.W. Han, et al.; Science 252, 576 (1991), Abstract;
Characterization of the L-arginine:nitric oxide pathway in human platelets: M.W. Radomski, et al.; Br. J. Pharmacol. 101, 325 (1990), Abstract;
The control of free arachidonic acid levels: R.D. Burgoyne & A. Morgan; TIBS 15, 365 (1990), Abstract;
The LDL receptor pathway delivers arachidonic acid for eicosanoid formation in cells stimulated by platelet-derived growth factor: A.J.R. Habenicht, et al.; Nature 345, 634 (1990), Abstract;
Kinetic analysis of the Ca2+-dependent, membrane-bound, macrophage phospholipase A2 and the effects of arachidonic acid: M.D. Lister, et al.; J. Biol. Chem. 263, 7506 (1988), Abstract; Full Text
Handbook of Eicosanoids: A.L. Willis (ed.); CRC Press, Boca Raton (1987),
Arachidonic acid metabolism: P. Needleman, et al.; Ann. Rev. Biochem. 55, 69 (1986), Abstract;

Related Literature

Brochures
Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

Technical Posters
Arachidonic Acid Metabolites
Arachidonic Acid Metabolites
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,