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Eicosapentaenoic acid

Inhibits PGE2 formation
 
BML-FA001-0100 100 mg 86.00 USD
 
BML-FA001-1000 1 g 376.00 USD
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Beneficial effect in cardiovascular diseases and inflammation. Inhibits PGE2 formation from arachidonic acid in 3T3 fibroblats.

Product Specification

Alternative Name:Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic acid (20:5, n-3), Icosapent
 
Formula:C20H30O2
 
MW:302.5
 
CAS:10417-94-4
 
Purity:≥98% (TLC)
 
Appearance:Colorless oil.
 
Solubility:Soluble in 100% ethanol.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. After opening, store under an inert atmosphere (e.g. N2 or argon) at -80°C. Stock solutions are stable for up to 2 months at -80°C under an inert atmosphere.
 
Handling:Protect from air.
 
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Product Literature References

Differential effects of n-6 and n-3 polyunsaturated fatty acids on cell growth and early gene expression in Swiss 3T3 fibroblasts: U. Danesch, et al.; J. Cell. Physiol. 168, 618 (1996), Abstract;
Eicosapentaenoic acid: its relevance in atherosclerosis and coronary artery disease: J. Mehta, et al.; Am. J. Cardiol. 59, 155 (1987), Abstract;
Eicosapentaenoic acid as a modulator of inflammation. Effect on prostaglandin and leukotriene synthesis: T. Terano, et al.; Biochem. Pharmacol. 35, 779 (1986), Abstract;
Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function: T.H. Lee, et al.; N. Engl. J. Med. 312, 1217 (1985), Abstract;

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