Fluorogenic substrate for tyrosinase. When assaying in phosphate buffer pH 7.1, the optimal excitation/emission wavelengths are 340/440 nm. 325/460 nm also work, but 380/460 nm will not detect this substrate.
Product Details
| Alternative Name: | 1-(4-Methyl-coumarin-7-yl)-3-(4-hydroxyphenyl)urea |
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| Formula: | C17H14N2O4 |
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| MW: | 310.3 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | Off-white solid. |
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| MeltingPoint: | 238-242°C |
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| Solubility: | Soluble in DMSO (18 mg/ml) or in methanol. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stable for at least 6 months after receipt when stored at -20°C. |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Discovery of small-molecule inhibitors of tyrosinase: J.P. Germanas, et al.; Bioorg. Med. Chem. Lett.
17, 6871 (2007),
Abstract;
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