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PAP-AMC, Tyrosinase substrate

 
BML-EI405-0100 0.1 mg 241.00 USD
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Fluorogenic substrate for tyrosinase. When assaying in phosphate buffer pH 7.1, the optimal excitation/emission wavelengths are 340/440 nm. 325/460 nm also work, but 380/460 nm will not detect this substrate.

Product Specification

Alternative Name:1-(4-Methyl-coumarin-7-yl)-3-(4-hydroxyphenyl)urea
 
Formula:C17H14N2O4
 
MW:310.3
 
Purity:≥98% (TLC)
 
Appearance:Off-white solid.
 
MeltingPoint:238-242°C
 
Solubility:Soluble in DMSO (18 mg/ml) or in methanol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 6 months after receipt when stored at -20°C.
 
Handling:Protect from light.
 
BML-EI405 Structure
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BML-EI405 Structure

Product Literature References

Discovery of small-molecule inhibitors of tyrosinase: J.P. Germanas, et al.; Bioorg. Med. Chem. Lett. 17, 6871 (2007), Abstract;

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