Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

BML-283

Pyruvate kinase M2 activator
 
BML-EI404-0005 5 mg Inquire for pricing
 
BML-EI404-0025 25 mg 149.00 USD
Do you need bulk/larger quantities?
 
Potent (AC50 = 0.111µM) and selective (over PKM1, PKR and PKL) activator of the tumor cell specific M2 isoform of pyruvate kinase (PKM2). Pyruvate kinase is a potential target for cancer chemotherapy. A useful new tool for altering aberrant glucose metabolism in cancer cells (Warburg effect).

Product Specification

Alternative Name:NCGC00030335, 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)-4-(4-methoxyphenylsulfonyl)-piperazine
 
Formula:C19H22N2O7S2
 
MW:454.5
 
Purity:≥98% (TLC)
 
Appearance:White solid.
 
MeltingPoint:229-231°C
 
Solubility:Soluble in DMSO (12mg/ml).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Use/Stability:Store, as supplied, at room temperature for up to one year.  Store solutions at -20°C for up to 3 months.
 
BML-EI404 Structure
Please mouse over
BML-EI404 Structure

Product Literature References

Evaluation of Substituted N,N'-Diarylsulfonamides as Activators of the Tumor Cell Specific M2 Isoform of Pyruvate Kinase: M. Boxer, et al.; J. Med. Chem. 53, 1048 (2010), Abstract;

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
Pyruvate kinase
By biological activity:
Pyruvate kinase Activator
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,