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PF-622

FAAH inhibitor
 
BML-EI402-0005 5 mg 114.00 USD
 
BML-EI402-0025 25 mg 411.00 USD
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Novel, potent and selective inhibitor of fatty acid amide hydrolase (FAAH). Inhibits FAAH in a time-dependent manner by covalently modifying the enzyme's active site serine (IC50=33nM). It is completely selective for FAAH relative to other mammalian serine hydrolases.

Product Specification

Alternative Name:N-phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carboxamide
 
Formula:C21H22N4O
 
MW:346.4
 
CAS:898235-65-9
 
Purity:≥98% (TLC)
 
Appearance:Off-white solid.
 
Solubility:Soluble in DMSO (7mg/ml) or 100% ethanol (3mg/ml).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Use/Stability:Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months.
 
BML-EI402 Structure
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BML-EI402 Structure

Product Literature References

Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity.: K. Ahn, et al.; Biochemistry 46, 13019 (2007), Abstract;

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