Novel, potent and selective inhibitor of fatty acid amide hydrolase (FAAH). Inhibits FAAH in a time-dependent manner by covalently modifying the enzyme's active site serine (IC50=33nM). It is completely selective for FAAH relative to other mammalian serine hydrolases.
Product Details
| Alternative Name: | N-phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carboxamide |
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| Formula: | C21H22N4O |
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| MW: | 346.4 |
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| CAS: | 898235-65-9 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | Off-white solid. |
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| Solubility: | Soluble in DMSO (7mg/ml) or 100% ethanol (3mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity.: K. Ahn, et al.; Biochemistry
46, 13019 (2007),
Abstract;
