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BML-282

UCH inhibitor
 
BML-EI400-0005 5 mg 119.00 USD
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Novel inhibitor of ubiquitin C-terminal hydrolase L1 (IC50 = 0.81 µM). It displays 21-fold greater selectivity over UCH-L3 (IC50 = 17 µM).

Product Specification

Alternative Name:N-(3,4-Dichlorobenzyl)-5-bromoisatin O-acetyloxime
 
Formula:C17H11BrCl2N2O3
 
MW:442.1
 
Purity:≥98% (TLC)
 
Appearance:Yellow solid.
 
Solubility:Soluble in DMSO (5mg/ml with warming) or dimethyl formamide (10mg/ml with warming).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year.  Store solutions at -20°C for up to 1 month.
 
Handling:Store tightly sealed. Allow product to equilibrate to room temperature prior to opening.
 
BML-EI400 structure
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BML-EI400 structure

Product Literature References

Mechanisms, biology and inhibitors of deubiquitinating enzymes: K.R. Love, et al.; Nat. Chem. Biol. 3, 697 (2007), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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