BML-277

Chk inhibitor



BML-EI388-0010	10 mg	95.00 USD

BML-EI388-0050	50 mg	381.00 USD

BML-277 is a highly selective inhibitor of Chk2 (IC₅₀=15nM) displaying <25% inhibition of 35 other kinases at 10µM). It displays potent radioprotective activity and prevents apoptosis of human T cells subjected to ionizing radiation (EC₅₀= 3-7.6µM). Useful tool for dissecting the role of Chk2 in cellular signaling.

Product Specification

Alternative Name:	Chk2 Inhibitor II

Formula:	C₂₀H₁₄ClN₃O₂

MW:	363.8

Purity:	≥98% (TLC)

Appearance:	Off-white solid.

CAS:	516480-79-8

Solubility:	Soluble in DMSO (20mg/ml) or ethanol (20mg/ml).

Long Term Storage:	-20°C

Background / Technical Information:	Please click here for the comprehensive product data sheet.