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(D-Pro1,2)-retro-(D-HIV-TAT(48-57))

Jnk inhibitor
 
BML-EI384-0001 1 mg 255.00 USD
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Useful as a control peptide in studies using D-JNKi1 (BML-EI355). This peptide is the cell transporter, and does not contain the JIP (JNK inhibitor peptide) sequence.

Product Specification

Sequence:H-DPro-DPro-DArg-DArg-DArg-DGln-DArg-DArg-DLys-DLys-DArg-Gly-NH2
 
MW:1589.5
 
Formulation:Lyophilized.
 
Purity:≥98% (TLC)
 
Appearance:Solid.
 
Solubility:Soluble in Water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Store as supplied, at -20ºC for up to 1 year. Store solutions at -20ºC for up to 3 months.
 

Product Literature References

Epidermal RAF prevents allergic skin disease: J. Raquz, et al.; Elife 5, e14012 (2016), Application(s): Animal studies and inhibitor treatment, Abstract; Full Text
D-JNKI1, a cell-penetrating c-Jun-N-terminal kinase inhibitor, protects against cell death in severe cerebral ischemia: L. Hirt, et al.; Stroke 35, 1738 (2004), Abstract; Full Text
Use of cell-permeable peptides to prevent neuronal degeneration: T. Borsello & C. Bonny; Trends Molec. Med. 10, 239 (2004), Abstract;
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia: T. Borsello, et al.; Nature Med. 9, 1180 (2003), Abstract;
Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death: C. Bonny, et al.; Diabetes 50, 77 (2001), Abstract; Full Text

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For Research Use Only. Not for use in diagnostic procedures.
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