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JX-401

p38 inhibitor
 
BML-EI366-0001 1 mg 57.00 USD
 
BML-EI366-0010 10 mg 141.00 USD
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Benzylpiperidine inhibitor of p38α (IC50 = 32 nM). Selective over p38γ (IC50 10 µM).

Product Specification

Alternative Name:1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine
 
Formula:C21H25NO2S
 
MW:355.5
 
CAS:349087-34-9
 
Purity:≥98% (TLC)
 
Appearance:Off-white solid.
 
Solubility:Soluble in DMSO (20 mg/ml) or ethanol (10 mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store as supplied, at -20ºC for up to 1 year. Store solutions at -20ºC for up to 3 months.
 
BML-EI366 structure
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BML-EI366 structure

Product Literature References

JX401, A p38alpha inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast: Y. Friedmann, et al.; Mol. Pharmacol. 70, 1395 (2006), Abstract;

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