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Geldanamycin-FITC

HSP90 inhibitor
 
BML-EI361-0001 1 mg 240.00 USD
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A novel geldanamycin fluorescent probe that may be used in a fluorescence polarization assay for HSP90 inhibitors. May also be used for detection of cell surface HSP90.

Product Specification

Formula:C55H63N5O13S
 
MW:1034.2
 
Purity:≥98% (TLC)
 
Appearance:Purple solid.
 
Solubility:Soluble in DMSO (>10mg/ml).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
BML-EI361 structure
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BML-EI361 structure

Product Literature References

Development of a fluorescence polarization assay for the molecular chaperone Hsp90: J. Kim, et al.; J. Biomol. Screen 9, 375 (2006), Abstract;
L.T. Gooljarsingh et al. Proc. Natl. Acad. Sci. USA 2006 103 7625: L.T. Gooljarsingh, et al.; Proc. Natl. Acad. Sci. USA 103, 7625 (2006), Abstract;
Synthesis of novel fluorescent probes for the molecular chaperone Hsp90: L. Llauger-Bufi, et al. ; Bioorg. Med. Chem. Lett. 13, 3975 (2003), Abstract;

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