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BIBB-515

Oxido-squalene cyclase inhibitor
 
BML-EI340-0010 10 mg 89.00 USD
 
BML-EI340-0050 50 mg 396.00 USD
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BIBB 515 is a potent and selective inhibitor of 2,3-oxidosqualene cyclase (OSC) in vivo. BIBB 515 inhibits LDL production in both normolipemic and hyperlipemic hamsters and may represent a novel approach for the development of lipid lowering drugs.

Product Specification

Formula:C22H21ClN2O2
 
MW:380.9
 
CAS:156635-05-1
 
Purity:≥98% (TLC)
 
Appearance:White solid.
 
Solubility:Soluble in DMSO (2mg/ml) or DMF (8mg/ml).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
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Product Literature References

Effects of a novel 2,3-oxidosqualene cyclase inhibitor on cholesterol biosynthesis and lipid metabolism in vivo: B. Eisele, et al.; J. Lipid. Res. 38, 564 (1997), Abstract; Full Text

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