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LM-4108

COX inhibitor
 
BML-EI331-0010 10 mg Inquire for pricing
 
BML-EI331-0050 50 mg 251.00 USD
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Selective COX-2 inhibitor (IC50=60nM).

Product Specification

Alternative Name:N-(2-Phenylethyl)Indomethacin amide
 
Formula:C27H25ClN2O3
 
MW:461.0
 
CAS:261766-32-9
 
Purity:≥98% (TLC)
 
Appearance:Pale yellow solid.
 
MeltingPoint:152-154°C
 
Solubility:Soluble in DMSO (25 mg/ml).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Use/Stability:Store solutions at -20ºC for up to 3 months.
 
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Product Literature References

Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors: A.S. Kalgutkar, et al.; PNAS 97, 925 (2000), Abstract;
Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors: A.S. Kalgutkar, et al.; J. Med. Chem. 43, 2860 (2000), Abstract;

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