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NSC-95397

CDC25 inhibitor
 
BML-EI309-0005 5 mg 135.00 USD
 
BML-EI309-0025 25 mg 572.00 USD
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A potent and selective inhibitor of Cdc25 phosphatase (Ki's for Cdc25A, B and C are 32, 96 and 40 nM respectively). NSC-95397 inhibits the growth of several human tumor cell lines and blocks G2/M cell cycle transition.

Product Specification

Formula:C14H14O4S2
 
MW:310.4
 
CAS:93718-83-3
 
Purity:≥98% (HPLC)
 
Appearance:Orange crystalline solid.
 
Solubility:Soluble in DMSO (50mM) or ethanol (5mM).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
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Product Literature References

Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors: J. S. Lazo, et al.; Mol. Pharmacol. 61, 720 (2002), Abstract; Full Text

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