Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 


COX inhibitor
BML-EI261-0005 5 mg 90.00 USD
BML-EI261-0025 25 mg 358.00 USD
Do you need bulk/larger quantities?
Replaces Prod. #: ALX-270-197

Cyclooxygenase inhibitor. Selectively inhibits PGH synthase-2 (IC50=1 µM) with no inhibition of PGH synthase-1 at concentrations up to 100 µM. Protects neuronal cultures from LPS-induced neurotoxicity.

Product Specification

Alternative Name:N-[2-(Cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide
Purity:≥98% (HPLC)
Solubility:Soluble in 100% ethanol (warm; sonication), DMSO (25mg/ml) or dimethyl formamide. Insoluble in water.
Long Term Storage:Ambient
Please mouse over

Product Literature References

Hypoxia potentiates tumor necrosis factor-α induced expression of inducible nitric oxide synthase and cyclooxygenase-2 in white and brown adipocytes: I. Bhattacharya, et al.; Biochem. Biophys. Res. Commun. 461, 287 (2015), Application(s): Cell Culture, Abstract;
Cyclooxygenase-2 inhibitors reverse chemoresistance phenotype in medullary thyroid carcinoma by a permeability glycoprotein-mediated mechanism: M.C. Zatelli, et al.; J. Clin. Endocrinol. Metab. 90, 5754 (2005), Abstract;
Constitutive cyclooxygenase (COX-1) and inducible cyclooxygenase (COX-2): rationale for selective inhibition and progress to date: D.E. Griswold & J.L. Adams; Med. Res. Rev. 16, 181 (1996), Abstract;
Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms: M. Ouellet & M.D. Percival; Biochem. J. 306, 247 (1995), Abstract;
Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase: J.K. Gierse, et al.; Biochem. J. 305 (Pt 2), 479 (1995), Abstract;
Purification and characterization of prostaglandin H synthase-2 from sheep placental cotyledons: J.L. Johnson, et al.; Arch. Biochem. Biophys. 324, 26 (1995), Abstract;
Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase: R.A. Copeland, et al.; PNAS 91, 11202 (1994), Abstract;
NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro: N. Futaki, et al.; Prostaglandins 47, 55 (1994), Abstract;
Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system: J. Barnett, et al.; Biochim. Biophys. Acta 1209, 130 (1994), Abstract;
Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic: J.L. Masferrer, et al.; PNAS 91, 3228 (1994), Abstract;
Effect of NS-398, a new nonsteroidal anti-inflammatory agent, on gastric ulceration and acid secretion in rats: I. Arai, et al.; Res. Commun. Chem. Pathol. Pharmacol. 81, 259 (1993), Abstract;
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions: N. Futaki, et al.; Gen. Pharmacol. 24, 105 (1993), Abstract;

Product Toolbox


Certificate of Analysis


By target:
By biological activity:
COX Inhibitor
By catalog section:


Technical Service
Customer Service

Recommend this page

For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,