AA-861

Lipoxygenase inhibitor



BML-EI216-0020	20 mg	80.00 USD

BML-EI216-0100	100 mg	315.00 USD

Potent, selective and orally active 5-lipoxygenase inhibitor. ID₅₀=0.8µM

Product Specification

MW:	326.4

Purity:	95%

CAS:	80809-81-0

Long Term Storage:	-20°C

Background / Technical Information:	Please click here for the comprehensive product datasheet.

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Product Literature References

Comparative protection against liver inflammation and fibrosis by a selective cyclooxygenase-2 inhibitor and a nonredox-type 5-lipoxygenase inhibitor: R. Horrillo, et al.; J. Pharmacol. Exp. Ther. 323, 778 (2007), Abstract;

Binding investigation of human 5-lipoxygenase with its inhibitors by SPR technology correlating with molecular docking simulation: L. Du, et al.; J. Biochem. 139, 715 (2006), Abstract;

Regulation of prostaglandin endoperoxide synthase-2 and IL-6 expression in mouse bone marrow-derived mast cells by exogenous but not endogenous prostanoids: B.L. Diaz, et al.; J. Immunol. 168, 1397 (2002), Abstract;