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KT5823

PKG inhibitor
 
BML-EI200-0100 100 µg 140.00 USD
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Replaces Prod. #: ALX-270-087

KT5823 is a derivative of K-252a and is a selective, cell permeable, inhibitor of PKG (Ki=0.234 µM). Ki’s for PKA =4μM and for MLCK=>10μM.

Product Specification

Formula:C29H25N3O5
 
MW:495.5
 
CAS:126643-37-6
 
Purity:≥98% (TLC)
 
Appearance:White solid.
 
Solubility:Soluble in DMSO (20mg/ml), dimethyl formamide (20mg/ml) and ethyl acetate (5mg/ml).
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Use/Stability:Store, as supplied, at 4°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
Handling:Protect from light.
 
bml-ei200
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Product Literature References

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases: H. Kase, et al.; Biochem. Biophys. Res. Commun. 142, 436 (1987), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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