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KT5720

PKA inhibitor
 
BML-EI199-0100 100 µg 149.00 USD
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Replaces Prod. #: ALX-270-075

KT5720 is a hexylester derivative of K-252a and is a selective inhibitor of PKA (Ki=0.056 µM). Cell permeable.

Product Specification

Formula:C32H31N3O5
 
MW:537.6
 
CAS:108068-98-0
 
Purity:≥98% (HPLC)
 
Appearance:White powder.
 
Solubility:Soluble in methanol: clear colorless solution at 5mg/ml.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
 
Handling:Protect from light.
 
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Product Literature References

Effects of insulin, insulin-like growth factor-I, and phorbol esters on neutral cholesteryl esterase activity in cultured rat vascular smooth muscle cells.: R. Fujiwara, et al.; J. Lab. Clin. Med. 126, 240 (1995), Abstract;
Effects of selective inhibition of protein kinase C, cyclic AMP-dependent protein kinase, and Ca(2+)-calmodulin-dependent protein kinase on neurite development in cultured rat hippocampal neurons: L. Cabell & G. Audesirk; Int. J. Dev. Neurosci. 11, 357 (1993), Abstract;
Multiple kinase arrest points in the G1 phase of nontransformed mammalian cells are absent in transformed cells.: D.M. Gadbois, et al.; Proc. Natl. Acad. Sci. USA 89, 8626 (1992), Abstract;
K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases: H. Kase, et al.; Biochem. Biophys. Res. Commun. 142, 436 (1987), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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