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ML-7 . HCl

Protein kinase inhibitor
BML-EI197-0010 10 mg 92.00 USD
BML-EI197-0050 50 mg 377.00 USD
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Replaces Prod. #: ALX-270-088

Potent and selective inhibitor of MLC kinase (Ki=0.3 µM). It inhibts also smooth-muscle myosin light chain kinase, protein kinase C (PKC) and cAMP-dependent protein kinase (PKA).

Product Specification

Alternative Name:1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine . HCl
Appearance:White solid.
Solubility:Soluble in DMSO (10mg/ml), ethanol/water (1:1, 10mg/ml), 100% ethanol (warm) and methanol.
Long Term Storage:-20°C
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Handling:Protect from light.
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Product Literature References

Dysregulation in Actin Cytoskeletal Organization Drives Increased Stiffness and Migratory Persistence in Polyploidal Giant Cancer Cells: B. Xuan, et al.; Sci. Rep. 8, 11935 (2018), Abstract;
Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase: M. Saitoh, et al.; J. Biol. Chem. 262, 7796 (1987), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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