Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

N-(p-Amylcinnamoyl)anthranilic acid

Inhibitor of PLA2 and TRP channels
BML-EI178-0050 50 mg 90.00 USD
BML-EI178-0250 250 mg 335.00 USD
Do you need bulk/larger quantities?
ACA is a close structural analog of the PLA2 inhibitor, ONO-RS-082 and possesses similar but less potent inhibitory activity. Inhibits TRP channels independently of PLA2, including TRPM2, TRPC6 and TRPM8. It is a useful tool for studying the physiological role of TRP channels.

Product Specification

Alternative Name:ACA
Purity:≥99% (HPLC)
Appearance:White solid.
Solubility:Soluble in DMSO (50 mg/ml) or ethanol (50 mg/ml @ 60°C).
Long Term Storage:Ambient
Use/Stability:Store, as supplied, at room temperature for up to 1 year. Make solutions fresh daily.
Please mouse over

Product Literature References

Development and validation of a cell-based high-throughput screening assay for TRPM2 channel modulators: Y. Song, et al.; J. Biomol. Screen. 13, 54 (2008), Abstract;
N-(p-amylcinnamoyl)anthranilic acid (ACA): a phospholipase A(2) inhibitor and TRP channel blocker: C. Hartenec, et al.; Cardiovasc. Drug Rev. 25, 61 (2007), Abstract;
Inhibition of TRPM2 cation channels by N-(p-amylcinnamoyl)anthranilic acid: R. Kraft, et al.; Br. J. Pharmacol. 148, 264 (2006), Abstract; Full Text
Inhibition of glucose-induced insulin secretion by the diacylglycerol lipase inhibitor RHC 80267 and the phospholipase A2 inhibitor ACA through stimulation of K+ permeability without diminution by exogenous arachidonic acid: P. Thams & K. Capito; Biochem. Pharmacol. 53, 1077 (1997), Abstract;
Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and dual role of epinephrine: H. S. Banga, et al.; Proc. Natl. Acad. Sci. USA 83, 9197 (1986), Abstract; Full Text

Related Literature

Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

Technical Posters
Arachidonic Acid Metabolites
Arachidonic Acid Metabolites
Download as PDF

All new literature pieces

Recommend this page

For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2019 Enzo Life Sciences, Inc.,