Replaces Prod. #: ALX-550-238
Bumetanide is a specific inhibitor of Na-K-2Cl cotransport. It binds specifically, saturably and with high affinity to membranes from a large variety of cells. A clinically useful diuretic.
Product Details
| Formula: | C17H20N2O5S |
| |
| MW: | 364.4 |
| |
| CAS: | 28395-03-1 |
| |
| Purity: | ≥98% |
| |
| Appearance: | White solid. |
| |
| Solubility: | Soluble in DMSO (25mg/ml) or 100% ethanol (10mg/ml). |
| |
| Shipping: | Ambient Temperature |
| |
| Long Term Storage: | Ambient |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
Product Literature References
Pharmacokinetics and pharmacodynamics of the diuretic bumetanide in the elderly: R. Oberbauer, et al.; Clin. Pharmacol. Ther.
57, 42 (1995),
Abstract;
Effect of bradykinin on Na-K-2Cl cotransport and bumetanide binding in aortic endothelial cells: J.D. Klein & W.C. O'Neill; J. Biol. Chem.
265, 22238 (1990),
Abstract;
The regulation of Na/K/2Cl cotransport and bumetanide binding in avian erythrocytes by protein phosphorylation and dephosphorylation. Effects of kinase inhibitors and okadaic acid: E.B. Pewitt, et al.; J. Biol. Chem.
265, 20747 (1990),
Abstract;
Characteristics and functions of Na-K-Cl cotransport in epithelial tissues: S.M. O'Grady, et al.; Am. J. Physiol.
253, C177 (1987),
Abstract;
