Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 


BML-EI113-0010 10 mg 224.00 USD
Do you need bulk/larger quantities?
Irreversible inhibitor of γ-glutamyl transpeptidase (GGT) ID50 = 0.54 mM. Inhibits the enzymatic conversion of leukotriene C4 to leukotriene D4. Displays antitumor and anti-metastatic activity. Blocks H. Pylori GGT-induced T-cell inhibition. Inhibits bioactivation/release of nitric oxide from GSNO.

Product Specification

Alternative Name:U-42126, AT-125
Purity:≥99% (HPLC)
Appearance:White solid.
Solubility:Soluble in water (max. 18mg/ml).
Long Term Storage:-20°C
Please mouse over

Product Literature References

Functional characterisation of glutathione export from the rat lens: A. Umapathy, et al.; Exp. Eye Res. 166, 151 (2018), Abstract;
A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System xc- Mediates Aglycemic Neuronal Cell Death: T.L. Thorn, et al.; ASN Neuro. 7, 1177 (2015), Application(s): Cell culture , Abstract; Full Text
A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase: J.B. King, et al.; J. Biol. Chem. 284, 9059 (2009), Abstract;
Inhibition of T-cell proliferation by Helicobacter pylori gamma-glutamyl transpeptidase: C. Schmees, et al.; Gastroenterology 132, 1820 (2007), Abstract;
Inhibition of gamma-glutamyl transpeptidase activity decreases intracellular cysteine levels in cervical carcinoma: P. Ruoso & D.W. Hedley; Cancer Chemother. Pharmacol. 54, 49 (2004), Abstract;
gamma-Glutamyl transpeptidase overexpression increases metastatic growth of B16 melanoma cells in the mouse liver: E. Obrador, et al.; Hepatology 35, 74 (2002), Abstract;
S-Nitrosoglutathione as a substrate for gamma-glutamyl transpeptidase: N. Hogg, et al.; Biochem. J. 323 (Pt2), 477 (1997), Abstract;
Metabolism and action of amino acid analog anti-cancer agents: G.S. Ahluwalia et al.; Pharmacol. Ther. 46, 243 (1990), Abstract;
Excretion of cysteine and gamma-glutamylcysteine moieties in human and experimental animal gamma-glutamyl transpeptidase deficiency: O.W. Griffith & A. Meister; PNAS 77, 3384 (1980), Abstract;
The inhibition of gamma-glutamyl transpeptidase from human pancreatic carcinoma cells by (alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501): L. Allen, et al.; Res. Commun. Chem. Pathol. Pharmacol. 27, 175 (1980), Abstract;

Related Literature

Technical Posters
Arachidonic Acid Metabolites
Arachidonic Acid Metabolites
Download as PDF

All new literature pieces

Recommend this page

For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2018 Enzo Life Sciences, Inc.,