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Leukotriene B4-dimethylamide

Prostanoid receptor ligand
 
BML-EI102-0050 50 µg 342.00 USD
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Leukotriene B4 antagonist. Inhibits binding of [3H]-LTB4 to guinea pig lung membranes (Ki=0.13 µM). Antagonizes the degranulation response to LTB4 in rabbit PMNL (Kd=0.2 µM) acting, most likely, via receptor desensitization. Partial agonist at higher concentrations (5 µM).

Product Specification

Formula:C22H37NO3
 
MW:363.5
 
CAS:83024-92-4
 
Concentration:50 µg/ml
 
Formulation:Solution in ethanol.
 
Purity:≥98% (HPLC)
 
Appearance:Liquid.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Use/Stability:Store as supplied (-80°C) for up to two years.
 
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Product Literature References

Modulation of ligand binding to leukotriene B4 receptors on guinea pig lung membranes by sulfhydryl modifying reagents: R. C. Falcone & D. Aharony, et al.; J. Pharmacol. Exp. Ther. 155, 565 (1990), Abstract;

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