1-Aminocyclobutane-cis-1,3-dicarboxylic acid

NMDA receptor agonist



BML-EA112-0005	5 mg	84.00 USD

BML-EA112-0025	25 mg	339.00 USD

Replaces Prod. #: ALX-550-013

The most potent and selective synthetic NMDA agonist known.

Product Specification

Formula:	C₆H₉NO₄

MW:	159.1

Purity:	≥99%

Appearance:	White solid.

CAS:	117488-23-0

Solubility:	Soluble in water.

Long Term Storage:	Ambient

Use/Stability:	Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months.

Handling:	Protect from light.

Background / Technical Information:	Please click here for the comprehensive product datasheet.

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Product Literature References

Inhibition of high affinity L-glutamic acid uptake into rat cortical synaptosomes by the conformationally restricted analogue of glutamic acid, cis-1-aminocyclobutane-1,3-dicarboxylic acid: E.J. Fletcher et al.; Neurosci. Lett. 121, 133 (1991), Abstract;

Cis-2,4-methanoglutamate is a potent and selective N-methyl-D-aspartate receptor agonist: T.H. Lanthorn et al.; Eur. J. Pharmacol. 182, 397 (1990), Abstract;

Synthesis and activity of a potent N-methyl-D-aspartic acid agonist, trans-1-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acids: R. Allan et al.; J. Med. Chem. 33, 2905 (1990), Abstract;