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AP4

NMDA receptor ligand
 
BML-EA101-0050 50 mg 34.00 USD
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NMDA agonist/antagonist. Synaptic depressant.

Product Specification

Alternative Name:DL-2-Amino-4-phosphonobutanoic acid
 
Formula:C4H10NO5P
 
MW:183.1
 
CAS:6323-99-5
 
Purity:≥99% (TLC)
 
Identity:Determined by NMR.
 
Appearance:White solid.
 
Solubility:Soluble in water (25mg/ml) or in dilute aqueous base.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:Ambient
 
Handling:Protect from light.
 
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Product Literature References

Anticonvulsant action of 2-amino-7-phosphonoheptanoic acid in the substantia nigra: G. De Sarro, et al.; Eur. J. Pharmacol. 106, 175 (1984), Abstract;
Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord: J. Davies & J.C. Watkins; Brain Res. 235, 378 (1982), Abstract;
The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations: R.H. Evans, et al.; Br. J. Pharmacol. 75, 65 (1982), Abstract;
2-amino-4-phosphonobutyric acid: a new pharmacological tool for retina research: M.M. Slaughter & R.F. Miller; Science 211, 182 (1981), Abstract;
Micromolar L-2-amino-4-phosphonobutyric acid selectively inhibits perforant path synapses from lateral entorhinal cortex: J.F. Koerner & C.W. Cotman; Brain Res. 216, 192 (1981), Abstract;
Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog: R.H. Evans, et al.; Br. J. Pharmacol. 67, 591 (1979), Abstract;

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