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25-Hydroxyvitamin D3

Ultra-high purity; Precursor to 1α,25-dihydroxyvitamin D3
 
BML-DM100-0001 1 mg 63.00 USD
 
BML-DM100-0005 5 mg 296.00 USD
Do you need bulk/larger quantities?
 
Intermediate in the biosynthesis of 1α,25-dihydroxyvitamin D3. Major circulating metabolite of vitamin D3.

Product Specification

Alternative Name:Calcifediol, 25-Hydroxycholecalciferol
 
Formula:C27H44O2
 
MW:400.6
 
CAS:19356-17-3
 
Purity:≥98% (HPLC)
 
Identity:Determined by IR.
 
Appearance:White to off-white crystalline solid.
 
Solubility:Soluble in 100% ethanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light and oxygen.
 
bml-dm100
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Product Literature References

Identification and characterization of a vitamin D3 decomposition product bactericidal against Helicobacter pylori: K. Hosoda, et al.; Sci. Rep. 5, 8860 (2015), Abstract; Full Text
Vitamin D promotes human extravillous trophoblast invasion in vitro: S.Y. Chan, et al.; Placenta 36, 403 (2015), Application(s): Cell Culture, Abstract;
Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells: M. Kongsbak, et al.; PLoS One 9, e96695 (2014), Abstract;
25-hydroxyvitamin D3 suppresses hepatitis C virus production: T. Matsumura, et al.; Hepatology 56, 1231 (2012), Application(s): Treatment of HCV-infected liver cells, Abstract;
Effect of 25-hydroxyvitamin D3 and 1α,25 dihydroxyvitamin D3 on differentiation and apoptosis of human osteosarcoma cell lines: L. Thompson, et al.; J. Orthop. Res. 30, 831 (2012), Application(s): Treatment of human osteosarcoma cell lines, Abstract;
Vitamin D metabolites and analogs induce lipoxygenase mRNA expression and activity as well as reactive oxygen species (ROS) production in human bone cell line: D. Somjen, et al.; J. Steroid. Biochem. Mol. Biol. 123, 85 (2011), Application(s): Treatment of human bone cells, Abstract;

General Literature References

Enzyme immunoassay for plasma 25-hydroxyvitamin D3 employing immunoaffinity chromatography as a pretreatment method: N. Kobayashi, et al.; J.Steroid Biochem. Mol. Biol. 44, 93 (1993),
Evidence for human placental synthesis of 24,25-dihydroxyvitamin D3 and 23,25-dihydroxyvitamin D3: L.P Rubin, et al.; Pediatr. Res. 34, 98 (1993),

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25-Hydroxyvitamin D2 

High purity vitamin D2 intermediate
21343-40-8, ≥98% (HPLC) | Print as PDF
 
BML-DM101-0001 1 mg 213.00 USD
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