Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

1-Oleoyl-2-acetyl-sn-glycerol

PKC activator
 
BML-DG125-0010 10 mg 117.00 USD
 
BML-DG125-0050 50 mg 470.00 USD
Do you need bulk/larger quantities?
 
Replaces Prod. #: ALX-300-300

In vitro potent activator of protein kinase C (PKC). Stimulator of secretion and aggregation in blood platelets. Stimulates formation of actin nucleation sites. Stimulation of pp60c-src phosphorylation in EBV transformed B-cells, 470μM.

Product Specification

Alternative Name:OAG
 
Formula:C23H42O5
 
MW:398.6
 
Source:Synthetic.
 
CAS:86390-77-4
 
Purity:≥98% (TLC)
 
Appearance:Colorless oil or waxy solid.
 
Solubility:Soluble in DMSO or ethanol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
 
bml-dg125
Please mouse over
bml-dg125

Product Literature References

New patterns of diacylglycerol metabolism in intact cells: J. Florin-Christensen; Biochem. J. 289, 783 (1993), Abstract;
Ca2+ and partly GTP gamma S-dependent particulate phospholipase C hydrolyzing phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate is inhibited by diacyl(acyl-acetyl) glycerols: E.W. Haeffner & U. Wittmann; J. Lipid Mediat. 5, 237 (1992), Abstract;
Diacylglycerol-stimulated formation of actin nucleation sites at plasma membranes: A. Shariff & E.J. Luna; Science 256, 245 (1992), Abstract;
Opposite effects of angiotensin II and the protein kinase C activator OAG on cardiac Na+ channels: I. Benz, et al.; J. Membr. Biol. 130, 183 (1992), Abstract;
Structural requirements of diacylglycerols for binding and activating phospholipid-dependent, Ca++-sensitive protein kinase: D.E. Kerr, et al.; Biochem. Biophys. Res. Commun. 148, 776 (1987), Abstract;
A possible role of protein kinase C in signal-induced lysosomal enzyme release: N. Kajikawa, et al.; BBRC 116, 743 (1983), Abstract;
Ca2+ and protein kinase C: Two synergistic cellular signals: B. Michell; Trends Biochem. Sci. 8, 263 (1983), (Review),
Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets: T.J. Rink, et al.; Nature 305, 317 (1983), Abstract;
Phorbol ester and diacylglycerol induce protein phosphorylation at tyrosine: T. Gilmore & G.S. Martin; Nature 306, 487 (1983), Abstract;
Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation: K. Kaibuchi, et al.; J. Biol. Chem. 258, 6701 (1983), Abstract; Full Text
Phosphatidylinositol turnover in platelet activation; calcium mobilization and protein phosphorylation: K. Kaibuchi, et al.; Cell Calcium 3, 323 (1982), Abstract;
Specificity of the fatty acyl moieties of diacylglycerol for the activation of calcium-activated, phospholipid-dependent protein kinase: T. Mori, et al.; J. Biochem. 91, 427 (1982), Abstract;

Related Literature

Brochures
Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

Technical Posters
Arachidonic Acid Metabolites
Arachidonic Acid Metabolites
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,