Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

1,2-Dioctanoyl-sn-glycerol (8:0)

PKC activator
 
BML-DG112-0020 20 mg 73.00 USD
 
BML-DG112-0100 100 mg 226.00 USD
Do you need bulk/larger quantities?
 
Replaces Prod. #: ALX-300-052

Potent activator of protein kinase C (PKC). Membrane permeable but non-physiologic DAG. Induces a discrete but transient translocation of protein kinase C.

Product Specification

Alternative Name:DOG
 
Formula:C19H36O5
 
MW:344.5
 
CAS:60514-48-9
 
Purity:≥96% (TLC)
 
Identity:Determined by 1H-NMR.
 
Appearance:Clear colorless oil or waxy solid.
 
Solubility:Soluble in DMSO or 100% ethanol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-80°C
 
Handling:At room temperature DOG is an oil. Due to its instability, keep it cool and dry.
 
Technical Info/Product Notes:Avoid acidic or basic conditions.
 
bml-dg112
Please mouse over
bml-dg112

Product Literature References

Chitosan Mediates Germling Adhesion in Magnaporthe oryzae and Is Required for Surface Sensing and Germling Morphogenesis: I.A. Geoghegan & S.J. Gurr; PLoS Pathog. 12, e1005703 (2016), Application(s): Germinations in the presence of chemical inducers of appressorium development, Abstract; Full Text
Uremic Toxins Induce ET-1 Release by Human Proximal Tubule Cells, which Regulates Organic Cation Uptake Time-Dependently: C.M. Schophuizen, et al.; Cells 4, 234 (2015), Application(s): Cell Culture, Abstract; Full Text
1,2-Dioctanoyl-glycerol induces a discrete but transient translocation of protein kinase C as well as the inhibition of MCF-7 cell proliferation: M. Issandou & J.M. Darbon; BBRC 151, 458 (1988), Abstract;
Further studies on the specificity of diacylglycerol for protein kinase C activation: M. Go, et al.; BBRC 144, 598 (1987), Abstract;
Structural requirements of diacylglycerols for binding and activating phospholipid-dependent, Ca++-sensitive protein kinase: D.E. Kerr, et al.; BBRC 148, 776 (1987), Abstract;
Activation of protein kinase C by Triton X-100 mixed micelles containing diacylglycerol and phosphatidylserine: Y.A. Hannun, et al.; J. Biol. Chem. 260, 10039 (1985), Abstract; Full Text
Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation: J.G. Ebeling, et al.; PNAS 82, 815 (1985), Abstract;
Diacylglycerols release LH: structure-activity relations reveal a role for protein kinase C: P.M. Conn, et al.; BBRC 126, 532 (1985), Abstract;
Exogenous sn-1,2-diacylglycerols containing saturated fatty acids function as bioregulators of protein kinase C in human platelets: E.G. Lapetina, et al.; J. Biol. Chem. 260, 1358 (1985), Abstract; Full Text
sn-1,2-Dioctanoylglycerol. A cell-permeable diacylglycerol that mimics phorbol diester action on the epidermal growth factor receptor and mitogenesis: R.J. Davis, et al.; J. Biol. Chem. 260, 1562 (1985), Abstract; Full Text

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
PKC
By biological activity:
PKC Activator
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Technical Posters
Arachidonic Acid Metabolites
Arachidonic Acid Metabolites
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,