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7-Hydroxy-DPAT . HBr

Dopamine receptor ligand
BML-D105-0050 50 mg 304.00 USD
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Replaces Prod. #: ALX-550-048

Selective D3 dopamine agonist (Ki=0.99 nM).

Product Specification

Formula:C16H25NO . HBr
Purity:≥98% (HPLC)
Identity:Determined by 1H-NMR and MS.
Appearance:White solid.
Solubility:Soluble in water or 100% ethanol.
Long Term Storage:Ambient
Use/Stability:Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months.
Handling:Protect from light.
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Product Literature References

Characterization of the human dopamine D3 receptor expressed in transfected cell lines: R.G. MacKenzie, et al.; Eur. J. Pharmacol. 266, 79 (1994), Abstract;
Expression and pharmacological characterization of the human D3 dopamine receptor: S.B. Freedman, et al.; J. Pharmacol. Exp. Ther. 268, 417 (1994), Abstract;
Behavioural effects of the putative D-3 dopamine receptor agonist 7-OH-DPAT in relation to other "D-2-like" agonists: S.A. Daly & J.L. Waddington; Neuropharmacology 32 Suppl 1, 509 (1993), Abstract;
Synthesis of (R,S)-trans-8-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetral in (trans-8-OH-PIPAT): a new 5-HT1A receptor ligand: Z.P. Zhuang, et al.; J. Med. Chem. 36, 1499 (1993), Abstract;
Identidication, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[2H} hydroxy-N,N-di-n-propyl-2-aminotetralin: D. Levesque, et al.; PNAS 89, 8155 (1992), Abstract;

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