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Cytochrome P450 2B6 (human) polyclonal antibody

 
BML-CR3295-0025 25 µl 100.00 USD
 
BML-CR3295-0100 100 µl 320.00 USD
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Product Specification

Alternative Name:CYP2B6
 
Host:Sheep
 
Immunogen:Synthetic peptide corresponding to aa 265-276 of human liver CYP2B6.
 
UniProt ID:P20813
 
Species reactivity:Human
 
Specificity:Recognizes human wild-type CYP2B6.1 and all known varients of CYP2B6.
 
Applications:IHC (FS), IHC (PS), WB
 
Formulation:Liquid. Neat serum containing no preservative.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Phenobarbital is well established as a potent inducer of cytochrome P-450 2B (CYP2B) expression, and work by different groups has shown that AP-1 might play a role in the induction process, and that insulin is able to supress the effect of phenobarbital. Human CYP2B6 appears to be the primary enzyme involved in the N-demethylation of S-mephenytoin and may contribute to the hepatic metabolism of toluene to benzyl alcohol.
 

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