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Cytochrome P450 1A2 (human) polyclonal antibody

 
BML-CR3130-0025 25 µl 108.00 USD
 
BML-CR3130-0100 100 µl 345.00 USD
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Product Specification

Alternative Name:CYP1A2
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the internal domain (aa 284-298) of human CYP1A2.
 
UniProt ID:P05177
 
Species reactivity:Human
 
Specificity:Recognizes human CYP1A1. Not suitable for use on rat tissue.
 
Applications:IHC (FS), IHC (PS), WB
 
Blocking Peptide:For Blocking peptide see Prod. No. BML-CP0123.
 
Formulation:Liquid. Serum containing 0.01% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Members of the cytochrome P-450 1A (CYP1A) sub-family are induced by a range of polycyclic aromatic compounds such as benzpyrene, 3-methylcholanthrene (Prod. No. BML-GR239), and pro-carcinogenic heterocyclic aromatic amines. Cigarette smoking has been reported to induce CYP1A2 in human liver, and appears to be a major catalyst in the hepatic activation of PhIP, (2-amino-1-methyl-6-phenylimidazo[4,5,b]-pyridine). The mono-oxygenase inhibitor inhibitor enoxacin induces CYP1A2 in rat liver, whereas a related compound ciprofloxacin does not.
 

Related Products

3-Methylcholanthrene 

Ah receptor ligand
56-49-5, ≥97% (TLC) | Print as PDF
 
BML-GR239-0010 10 mg 66.00 USD
 
BML-GR239-0050 50 mg 270.00 USD
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Blocking peptide for Cytochrome P450 1A2 (human) pAb (Prod. No. BML-CR3130) 

≥95% | Print as PDF
 
BML-CP0123-0100 100 µg 59.00 USD
Do you need bulk/larger quantities?
 

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