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Cytochrome P450 1A1 (rat) polyclonal antibody

 
BML-CR3115-0025 25 µl 100.00 USD
 
BML-CR3115-0100 100 µl 320.00 USD
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Product Specification

Alternative Name:CYP1A1
 
Host:Sheep
 
Immunogen:Synthetic peptide corresponding to a portion of C-terminal rat CYP1A1.
 
UniProt ID:P00185
 
Species reactivity:Rat
 
Specificity:Recognizes rat CYP1A1. Not suitable for use on human tissue.
 
Applications:IHC (FS), IHC (PS), WB
 
Blocking Peptide:For Blocking peptide see Prod. No. BML-CP0111.
 
Formulation:Liquid. Serum containing 0.01% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Members of the cytochrome P-450 1A (CYP1A) sub-family are induced by a range of polycyclic aromatic compounds such as benzpyrene, 3-methylcholanthrene (Prod. No. BML-GR239), and pro-carcinogenic heterocyclic aromatic amines. Such compounds have been reported to induce CYP1A1 in rat liver, human placenta and lung. A rare polymorphism of the CYP1A1 gene has been implicated in familial Parkinson's Disease (PD), whereas in the rat, CYP1A1 has been localized to the globus pallidus, but not to the substantia nigra where cell death associated with the pathology of PD occurs.
 

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Blocking peptide for Cytochrome P450 1A1 (rat) pAbs (Prod. No. BML-CR3110, BML-CR3115) 

≥95% | Print as PDF
 
BML-CP0111-0100 100 µg 59.00 USD
Do you need bulk/larger quantities?
 

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