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JWH-015

CB2 receptor agonist
 
BML-CR109-0025 25 mg 316.00 USD
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Replaces Prod. #: ALX-550-385

Selective cannabinoid CB2 agonist. (Ki=13.8 and 383 nM for CB2 and CB1 receptors respectively). Anti-proliferate effects in PC-3 cells.

Product Specification

Formula:C23H21NO
 
MW:327.4
 
CAS:155471-08-2
 
Purity:≥98% (TLC)
 
Appearance:White to off-white powder
 
Solubility:Soluble in 100% ethanol (8mg/ml) or DMSO (3mg/ml)
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
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Product Literature References

The search for selective ligands for the CB2 receptor: J.W, Huffman; Curr. Pharm. Des. 6, 1323 (2000), Abstract;
Pharmacology of cannabinoid receptor ligands: R.G. Pertwee ; Curr. Med. Chem. 6, 635 (1999), Abstract;
The third transmembrane helix of the cannabinoid receptor plays a role in the selectivity of aminoalkylindoles for CB2, peripheral cannabinoid receptor: C.N. Chin et al.; J. Pharmacol. Exp. Ther. 291, 837 (1999), Abstract;
Evidence for the presence of CB2-like cannabinoid receptors on peripheral nerve terminals: G. Griffin et al.; Eur. J. Pharmacol. 339, 53 (1997), Abstract;

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