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BML-190

Cannabinoid receptor ligand
 
BML-CR104-0010 10 mg Inquire for pricing
 
BML-CR104-0050 50 mg 229.00 USD
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A potent and selective ligand for the human cannabinoid CB2 receptor. Inhibits LPS-induced COX-2 induction. Also inhibits LPS-induced monocytic cell neurotoxicity.

Product Specification

Formula:C23H23ClN2O4
 
MW:426.9
 
CAS:2854-32-2
 
Purity:≥98% (TLC)
 
Appearance:Off-white solid.
 
Solubility:Soluble in DMSO(25mg/ml) or DMF(25mg/ml).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
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Product Literature References

BML-190 and AM251 act as inverse agonists at the human cannabinoid CB2 receptor: signalling via cAMP and inositol phosphates: D. C. New, et al.; FEBS Lett. 536, 157 (2003), Abstract;
Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor: A. Klegeris, et al.; Br. J. Pharmacol. 139, 775 (2003), Abstract; Full Text
Effects of cannabinoids on LPS-stimulated inflammatory mediator release from macrophages: involvement of eicosanoids: Y. H. Chang, et al.; J. Cell. Biochem. 81, 715 (2001), Abstract;

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