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Furoxan

Releases NO in the presence of thiols
 
BML-CN255-0050 50 mg Inquire for pricing
 
BML-CN255-0010 10 mg Inquire for pricing
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A novel NO donor which only releases NO in the presence of thiols. It is a potent vasodilator and inhibitor of platelet aggregation.

Product Specification

Alternative Name:4-Phenyl-3-furoxancarbonitrile
 
Formula:C9H5N3O2
 
MW:187.2
 
CAS:125520-62-9
 
Purity:≥99% (HPLC)
 
Appearance:White solid.
 
MeltingPoint:72-74°C
 
Solubility:Soluble in ethanol (25 mg/ml) or DMSO (25 mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
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Product Literature References

A new class of furoxan derivatives as NO donors: mechanism of action and biological activity: R. Ferioli, et al.; Br. J. Pharmacol. 114, 816 (1995), Abstract; Full Text
Furoxans as nitric oxide donors. 4-Phenyl-3-furoxancarbonitrile: thiol-mediated nitric oxide release and biological evaluation: C. Medana, et al.; J. Med. Chem. 37, 4412 (1994), Abstract;

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