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Sp-8-Br-cGMPS

cGMP agonist
 
BML-CN217-0500 500 µg 61.00 USD
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Replaces Prod. #: ALX-480-027

Cell-permeable, phosphodiesterase-resistant cGMP agonist. This analog activates PKA and PKG with similar potency. Much more lipophilic and membrane permeant as compared to cyclic GMP (Prod. No. ALX-480-059) or Sp-cGMPS (Prod. No. ALX-480-073)

Product Specification

Formula:C10H10BrN5O6PS . Na
 
MW:462.2
 
CAS:153660-03-8
 
Purity:≥98% (HPLC)
 
Appearance:Lyophilized solid.
 
Solubility:Soluble in water (25mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
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Product Literature References

Evidence for two intracellular calcium pools in Dictyostelium: the cAMP-induced calcium influx is directed into a NBD-Cl- and 2,5-di-(tert-butyl)1,4-hydroquinone-sensitive pool: H. Flaadt et al.; J. Cell. Sci. 105 ( Pt 4), 1131 (1993), Abstract;

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PKG
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