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CCCP

MPTP inhibitor
 
BML-CM124-0500 500 mg 124.00 USD
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A potent uncoupler of mitochondrial oxidative phosphorylation. CCCP is a useful tool for depolarizing mitochodrial membrane potential.

Product Specification

Alternative Name:(3-Chlorophenyl)hydrazonomalonitrile
 
Formula:C9H5ClN4
 
MW:204.6
 
CAS:555-60-2
 
Purity:≥98% (TLC)
 
Identity:Determined by IR.
 
Appearance:Yellow-orange solid.
 
Solubility:Soluble in DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
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Product Literature References

Depolarization evokes different patterns of calcium signals and exocytosis in bovine and mouse chromaffin cells: the role of mitochondria: E. Ales, et al.; Eur. J. Neurosci. 21, 142 (2005), Abstract;
Mechanisms of diethylstilbestrol-induced calcium movement in MG63 human osteosarcoma cells: Y.-C. Chen, et al.; Toxicol. Lett. 122, 245 (2001), Abstract;

General Literature References

Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria: A. A. Gerencser, et. al.; J. Physiol. 590, 2845 (2012), Abstract; Full Text

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