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CGP-37157

MPTP inhibitor
 
BML-CM119-0005 5 mg 106.00 USD
 
BML-CM119-0025 25 mg 422.00 USD
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Potent, selective inhibitor of mitochondrial Na+Ca2+ exchange. IC50=0.4µM. Blocks mitochondrial permeability transition.

Product Specification

Formula:C15H11Cl2NOS
 
MW:324.2
 
CAS:75450-34-9
 
Purity:≥98% (TLC)
 
Appearance:White solid.
 
Solubility:Soluble in DMSO.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
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Product Literature References

Mitochondria fine-tune the slow Ca2+ transients induced by electrical stimulation of skeletal myotubes: V. Eisner, et al.; Cell Calcium 48, 358 (2010), Abstract;
Selectivity of inhibition of Na(+)-Ca2+ exchange of heart mitochondria by benzothiazepine CGP-37157: D. A. Cox, et al.; J. Cardiovasc. Pharmacol. 21, 595 (1993), Abstract;

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